The clinical and pathological background of two cases of oxalosis.

The deposition of calcium oxalate crystals in human tissues was first described by Lepoutre (1925), who found these in the kidney of a child aged 41 years who also had multiple urethral, ureteric, and bilateral renal calculi. Similar deposits have been described in the kidneys and elsewhere by other authors. Ying Chou and Donohue (1952) suggested the term " oxalosis " to describe the condition in which these crystalline deposits occur, and Scowen, Stansfeld, and Watts (1959) have used it for cases with disseminated extrarenal calcium oxalate deposits. This, though rare, has been identified with greater frequency in recent years. Two further cases are reported here; though they recapitulate many known features of the condition they present some that